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In hepatocytes and adipocytes it reduces the activity of key lipogenic enzymes: Acetyl-CoA carboxylase (ACC) , a key step in fatty acid synthesis Fatty acid synthase (FAS) , the enzyme creating long chains of fatty acids Lipoprotein lipase (LPL) in adipocytes, reduces uptake of circulating triglycerides into fat cells Imagine it as turning valves in a pipeline, you close the inflow (lipogenesis), open the outflow (lipolysis)
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Outcomes were intraprocedural and early stent patency (24 hours), recanalization status (mTICI 2c3), safety outcomes, including symptomatic intracranial hemorrhage (sICH) and functional outcomes (90d-mRS)
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